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Adhesion of type A Pasteurella mulocida to rabbit pharyngeal cells

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Adhesion of type A Pasteurella mulocida to rabbit pharyngeal cells
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Rabbit Anatomy - Digestive System rabbit digestive system

Rabbit Anatomy - Digestive System

As total herbivores, rabbits have an extremely long digestive tract in order to process their food in the most efficient way.
The whole of a rabbit anatomy has evolved to survive on a very poor diet, the digestive tract especially. A special feature of the process, known as caecotrophy, is a remarkable way the rabbit 'recycles' waste faecal matter in order to extract any nutrients that may have been missed on the first, second or even third time round in the digestion system. (See below for more on this).

The whole digestive system of the rabbit is huge and may account for between 10-20 per cent of its total body weight.
Let's follow the process through the rabbit's anatomy...
Stomach
In an adult rabbit the total length of the alimentary canal is 4.5 to 5 m. After a short oesophagus there is a simple stomach which stores about 60-80 g of a rather pasty mixture of feedstuffs.
Food eaten by the rabbit quickly reaches the stomach where it remains for a few hours, and although in an acid environment it has little chemical change.
Liver & Pancreas
Two major glands secrete into the small intestine: the liver and the pancreas.
Bile from the liver contains bile salts and many organic substances but no enzymes. Bile aids digestion catalytically.
The reverse is true of pancreatic juice which contains a sizable quantity of digestive enzymes allowing the breakdown of proteins (trypsin, chymotrypsin), starch (amylase) and fats (lipase).
Small Intestine
If the small intestine of a rabbit was laid out it would be more than 10 times the length of the rabbit.
The contents of the stomach are gradually 'injected' into the small intestine in short bursts, by strong stomach contractions.
The small intestine is about 3 m long and nearly 1 cm in diameter. The contents are liquid, especially in the upper part. Normally there are small tracts, about 12 cm long, which are empty. The small intestine ends at the base of the caecum. This second storage area is about 40-45 cm long with an average diameter of 3-4 cm. It contains 100-120 g of a uniform pasty mix with a dry matter content of about 20 percent.
As the contents enter the small intestine they are diluted by the flow of bile, the first intestinal secretions and finally the pancreatic juice.
After enzymatic action from these last two secretions the elements that can easily be broken down are freed and pass through the intestinal wall to be carried by the blood to the cells.
Large Intestine
The large intestine is made up of the caecum and colon. The caecum is very large, (about 10 times the volume of the stomach, and about 40 per cent of the total volume of the gastrointestinal tract).
The colon separates the large and small fibre particles. The large particles of indigestible fibre are moved straight through the colon to form the hard droppings. the smaller fibre particles and other small incomplete digested food particles are moved backwards (by special muscles in the colon called haustrae).
This 'slurry' enters the caecum where it is broken down and fermented.
Caecum
The particles that are not broken down in the small intestine enter the caecum after less than 2 hours. There they have to stay for about 2 to 12 hours, while they are attacked by bacterial enzymes.
Elements which can be broken down by this new attack (mainly volatile fatty acids) are freed and in turn pass through the wall of the digestive tract and into the bloodstream.
Very near the end of the small intestine, at the entrance to the caecum, begins the exit to the colon. The caecum has a blind pouch branching off from the small intestine-colon axis. Physiological studies show that this blind pouch-reservoir forms part of the digestive tract: the contents circulate from the base to the tip passing through the centre of the caecum, then return towards the base, along the wall.
The content of the caecum is then evacuated into the colon. Approximately half consists of both large and small food particles not already broken down, while the other half consists of bacteria that have developed in the caecum, fed on matter from the small intestine.
Colon
The colon is about 1.5 m and follows on from the caecum, it is creased and dented for about 50 cm (proximal colon) and smooth in the terminal section (distal colon).
The rabbit's digestive tract is virtually the same as that of other monogastric animals, however in the rabbit anatomy, the digestive tract has a uniqueness that lies in the dual function of the proximal colon.
If the caecum content enters the colon in the early part of the morning it undergoes few biochemical changes.
If the caecal content enters the colon at another time of day the reaction of the proximal colon is entirely different.

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